The chapter on caffeine has some interesting stuff, especially the personal account of an attempt at abstinence and the chemistry of how caffeine works, but it feels a bit padded with historical stuff that I knew already and I think is widely written about.
The mescaline one was shorter, less padded, and took on some interesting issues about the relationship between drug reform advocates who want to 'decriminalize plants', and Native Americans who want to preserve their own privileged and restricted access to the mescaline-bearing cacti, which is culturally and spiritually significant to them (but as part of a relatively recent made-up religion). Again, a great read, and of course he writes brilliantly about his own mescaline and peyote experiences, while acknowledging the difficulty of writing about such things.
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